The transplant team must resuscitate the heart until it meets strict transplant criteria. Mayo Clinic in Arizona heart transplant specialists say the heart-in-a-box perfusion system analyzes the heart's hemodynamic parameters, monitoring every 15 to 30 minutes as if it were a patient in the ICU. The system's measurements also give transplant professionals an opportunity to confirm the heart's function before accepting it for transplant. When transplant specialists place a retrieved donor organ in the heart-in-a-box machine, it perfuses the organ with warm, oxygenated blood, reviving the heart from nonbeating to beating status. In addition, the heart-in-a-box has the potential to widen the donor pool by supporting the novel use of donation after circulatory death (DCD) hearts by reviving and supporting the recovery of nonbeating hearts. However, the new system preserves a heart while it is beating, extending the time between retrieval and transplant by several hours. The standard heart preservation technique preserves a heart for a window of approximately 3 to 5 hours. New perfusion system preserves a heart while it is beating, extending the time between retrieval and transplant by several hours.
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